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8.000.6107

USP Modernization Initiative: Ionic Impurities in Drug Substances by Ion Chromatography


Summary

This poster presented jointly with USP at AAPS meeting shows, that we successfully validated an IC method to determine chloride and sulfate in drug substances, potassium bicarbonate and potassium carbonate. The proposed IC method overcomes limitations of the turbidimetry/visual comparison methods.

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