Phosphite and phosphate in Pamidronate suppressed conductivity detection
AN-S-369
pt_PT
<p>Pamidronate is applied to treat osteoporosis by strengthening the bones. It is a bisphosphonate containing a primary amine group. Phosphite and phosphate are related compounds, which need to be quantified. USP requires the use of formic acid eluent with refractive index detection. But a standard IC procedure offers an alternative with better sensitivity. Phosphite and phosphate are analyzed with conductivity detection after sequential suppression.</p>
Pamidronate is applied to treat osteoporosis by strengthening the bones. It is a bisphosphonate containing a primary amine group. Phosphite and phosphate are related compounds, which need to be quantified. USP requires the use of formic acid eluent with refractive index detection. But a standard IC procedure offers an alternative with better sensitivity. Phosphite and phosphate are analyzed with conductivity detection after sequential suppression.