Filtro de Aplicações
- WP-037Simplifying quality control using Near-Infrared Spectroscopy
Quality control is impacted by multiple challenges, which can have an influence on the functioning of the QC lab. The present White Paper provides approaches, how to simplify the daily quality control using near-infrared spectroscopy combined with a dedicated smart software like Vision Air.
- WP-011Sustainable Testing of Paint and Coatings
More strict regulations paired with more complex products have increased testing complexity in the paint and coating industry. Therefore, producers ask for more powerful, safe and sustainable analytical methods. Testing by Vis-NIR spectroscopy is a sustainable and costefficient alternative to many wet chemical methods. This white paper describes how Vis-NIR spectroscopy improves testing procedures for various analyses during the formulation and production of paint and coatings in an economic and ecological way. Key words: testing, sustainable, VOC, paint, coating, binders, resins, additives, pigments, solvents
- WP-023Karl Fischer titration and near-infrared spectroscopy in perfect synergy
Metrohm has shaped moisture analysis for more than half a century. Find out about new developments in water analysis and learn how near-infrared spectroscopy in combination with Karl Fischer titration can increase your sample throughput and boost your productivity.
- WP-026Surface Enhanced Raman Scattering (SERS) – Expanding the Limits of Conventional Raman Analysis
Surface Enhanced Raman Scattering or SERS is an anomalous enhancement of Raman scattering when molecules are adsorbed to gold or silver nanoparticles – this enhancement can be as large as 107. The advantage of SERS for the analytical chemist lies in its ability to detect analyte concentrations of parts per million and even parts per billion levels, while classical Raman is limited to parts per thousand. Metrohm Raman produces P-SERS assays in the form of nanoparticles printed onto substrates using inkjet technology. This method produces inexpensive test strips that exhibit exceptional stability and sensitivity. There are two markets that can be easily addressed with P-SERS: forensic analysis and food safety. This white paper explains the mechanism of SERS and how it can be applied to handheld Raman analysis with Metrohm Raman Mira systems.
- WP-030Analytical method transfer
Near-infrared spectroscopy (NIRS) is a widely used analytical technique for qualitative and quantitative analysis of various products in research and industrial applications. Because of different reasons it might be necessary to transfer analytical methods from one NIR analyzer to another one. This white paper summarizes the workflow of such method transfer.
- WP-034Determination of Heroin in Street Drug Samples
Printable Surface Enhanced Raman Scattering (P-SERS) silver substrates were used with Metrohm Raman’s Mira DS handheld Raman analyzer to successfully detect heroin in 18 crude street heroin samples. Detection of heroin with P-SERS was accomplished easily and very quickly, with minimal sample clean-up. Solvent studies were also implemented to determine the optimal solvent for crude sample extraction, with results included here.
- WP-036ENLean manufacturing of polyurethane, assisted by near-infrared (NIR) and Raman spectroscopy
Chemical manufacturing such as polyurethane production is characterized by a cost intensive production process combined with a negative ecological impact. These adverse effects can be significantly improved by using vibrational spectroscopy. This analytical technique can assist the operator of the plant to reduce costs and minimize the impact on the environment as is demonstrated in the present white paper.
- WP-038FDA 21 CFR Part 11 Compliance by Metrohm Raman
Norms and Standards 21 CFR Part 11 is the FDA rule relating to the use of electronic records and electronic signatures. Recognizing the increasing impact of electronic media on critical data in regulated environments, the FDA met with members of the pharmaceutical industry in the early 1990s. The pharmaceutical industry and the FDA were interested in how they could accommodate paperless record systems and ensure the reliability, trustworthiness, and integrity of electronic records.
- WP-042Data Integrity with NIR-Spectroscopy Software
Data Integrity is currently a hot topic issue that has created much attention and has raised concern within companies working in regulated environments. This White Paper explains some of the key terms used in the context of Data Integrity and outlines how the requirements of Data Integrity can be understood and implemented.
- WP-046Overcoming the aqueous limitation at NIR Spectroelectrochemistry
NIR spectroscopy has been traditionally limited due to the water absorption in this spectral range. In this way, the well-known water restriction has limited the development of new applications for NIR spectroelectrochemistry. In this work, several interesting alternatives are proposed in order to minimize or even to remove the aqueous contribution in this spectral range.