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Good vibes in your lab: State-of-the-art near-infrared spectrometer for easier, faster, and more efficient quality control and routine screening.

PTRam Analyzer

Inline self-calibrating process development Raman.

DS2500 Analyzers

Compact and robust: Near-infrared spectrometers for fast and cost-effective quality control and routine screening of liquid or solid samples.

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Product models (3)

2.922.1000

NIRS DS2500 Polymer Analyzer

Robust near-infrared spectroscopy for quality control of polymers, not only in laboratories, but also in production environments.The NIRS DS2500 Polymer Analyzer is the tried and tested, flexible solution for quality control and routine analysis of PE, PP, PET, polyamide, and other polymers in solid form along the entire production chain. Resistant to dust, moisture, vibrations, and temperature fluctuations, the NIRS DS2500 Polymer Analyzer is not only suitable for laboratory use, but also use in harsh production environments.The NIRS DS2500 Polymer Analyzer covers the full spectral range from 400 to 2,500 nm and delivers accurate results in less than one minute. The NIRS DS2500 Polymer Analyzer is ready for immediate use through pre-calibrations for PE, PP, PET, and polyamide (PA 6) and, thanks to its simple operation, supports users in their day-to-day routine tasks.

2.929.1000

NIRS DS2500 Polyol Analyzer

Robust, near-infrared spectroscopy for quality control of polyols, not only in laboratories, but also in production environments. The NIRS DS2500 Polyol Analyzer is the tried and tested, flexible solution for quality control and routine analysis of polyols and is compliant with the standards ASTM D6342-12 and ISO 15063:2011. Its robust design makes the NIRS DS2500 Polyol Analyzer resistant to dust, moisture, and vibrations, which means that it is highly suitable for use in harsh production environments.The NIRS DS2500 Polyol Analyzer covers the full spectral range from 400 to 2,500 nm, heats samples up to 80 °C, and delivers accurate results in less than one minute. The NIRS DS2500 Polyol Analyzer is ready for immediate use through pre-calibration for polyols and, thanks to its simple operation, supports users in their day-to-day routine tasks.

2.929.2000

NIRS DS2500 Petro Analyzer

Robust near-infrared spectroscopy for quality control of fuels, not only in laboratories but also in direct production environments. The NIRS DS2500 Petro Analyzer is the tried and tested, flexible solution for quality control and routine analysis of fuels and is compliant with the standard ASTM D6122. Resistant to dust, moisture, and vibrations, the NIRS DS2500 Petro Analyzer is not only suitable for laboratory use, but also use in direct production environments.The NIRS DS2500 Petro Analyzer covers the full spectral range from 400 to 2,500 nm and delivers accurate results in less than one minute. The NIRS DS2500 Petro Analyzer is ready for immediate use through pre-calibrations for gasoline, diesel, and kerosine and, thanks to its simple operation, supports users in their day-to-day routine tasks. In cases of larger-sized sample quantities, productivity can be considerably increased by using a flow-through cell in combination with a Metrohm sample robot.

Tried-and-tested applications

Applications (73)

AN-NIR-011

Transferability of a calibration model for caffeine on the NIRS XDS Rapid Content Analyzer

This Application Note demonstrates that a calibration model for caffeine and microcrystalline cellulose developed on the NIRS XDS Rapid Content Analyzer (RCA) is transferable to other NIRS XDS RCA. Due to the improved signal-to-noise ratio, reduced bandwidth and improved wavelength precision of the NIRS XDS, the transferability of the calibration model can be easily and efficiently performed.

AN-NIR-012

Increase the accuracy of your NIR measurements with instrument calibration

This Application Note describes how the accuracy of your NIR measurements can be increased with instrument calibration.

WP-043

Instrument Calibration, System Verification, and Performance Validation for Metrohm Instant Raman Analyzers (Mira)

Analytical Instrument Qualification (AIQ) according to the United States Pharmacopeia (USP) ensures that instruments perform as intended and users may have confidence in data quality. As the Pharma industry adopts handheld Raman instruments for incoming materials identification and verification, producers of such systems must provide suitable calibration and validation routines. Upon completion of these tests, end users are assured that all measurements are in accordance with agreed standards at Metrohm Raman, we have sophisticated AIQ routines in place to confirm the quality of your results.

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73 Applications

AN-PAN-1060
Inline process monitoring of moisture content in tetrahydrofuran
This Process Application Note presents a method to accurately monitor low levels of moisture in tetrahydrofuran (THF) in «real-time» safely, reliably, and optimally with a 2060 The NIR Analyzer from Metrohm Process Analytics. Due to the hazardous and hygroscopic nature of THF, a single explosion-proof inline process analyzer is the preferred solution for industries to reduce chemical treatment, improve product quality, and increase profits.
AN-NIR-064
Quality control of ammonium nitrate
Specialty chemicals have to fulfill multiple quality requirements. One of these quality parameters, which can be found in almost all certificates of analysis and specifications, is the moisture content. The standard method for the determination of moisture content is Karl Fischer titration.This method requires reproducible sample preparation, chemicals, and waste disposal. Alternatively, near-infrared spectroscopy (NIR) can be used for the determination of moisture content. With this technique, samples can be analyzed without any preparation and without using any chemicals.
AN-NIR-054
Quality Control of Shampoo
Determination of sodium laureth sulfate (SLES), cocamidopropyl betaine (CABP), cocamidopropylamine oxide (CAW), cocamide diethanolamine (DEA), and carbopol in shampoo is a cost- and time-intensive process due to the use of large volumes of chemicals per analysis. This application note demonstrates that the DS2500 Solid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a cost-efficient and fast solution for a simultaneous determination these parameters in shampoo. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for the complete analysis in less than a minute.
AN-NIR-035
Quality Control of Polyols
Toxic and corrosive chemicals such as p-toluenesulfonyl isocyanate (TSI) and tetrabutylammonium hydroxide are used for the Hydroxyl Number analysis of polyols by titration according to ASTM D4274-16. This application note demonstrates how the XDS RapidLiquid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a cost-efficient and fast solution for the determination of the hydroxyl (OH) number of polyols. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for the analysis of polyols in less than a minute.
AN-NIR-081
Quality Control of Polyethylene
Determination of the density of polyethylene (PE) (ASTM D792) is normally a challenging procedure due to reproducibility difficulties. Measurement via FT-IR can be problematic when larger sample sizes must be analyzed due to sample inhomogeneity. This application note demonstrates that the DS2500 Solid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a reliable and fast solution for determination of the density of PE. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows the analysis of larger, inhomogeneous sample sizes of PE in less than a minute.
AN-NIR-091
Quality Control of Mixed Acetic, Hydrofluoric, and Nitric Acids
This application note discusses an alternative near-infrared (NIR) spectroscopy method that can reliably determine all parameters within a minute, even in complex acid mixtures.
AN-NIR-060
Quality Control of Polyamides
Functional group and viscosity analysis (ASTM D789) of polyamides can be a lengthy and challenging process due to the sample’s limited solubility. This application note demonstrates that the DS2500 Solid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a cost-efficient and fast solution for a simultaneous determination of the intrinsic viscosity as well as the amine, carboxylic, and moisture content in polyamides. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for the analysis of polyamides in less than a minute.
AN-NIR-071
Automated acid number determination in lubricants with near-infrared spectroscopy
Acid Number (AN) analysis of lubricants (ASTM D664) can be a lengthy and costly process due to usage of large amounts of chemicals and required cleaning steps of the analytical equipment between each measurement. This application note demonstrates that the XDS RapidLiquid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a cost-efficient, fast alternative for the determination of the acid number of lubricants. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for the analysis of AN in less than a minute.
AN-NIR-023
Quality Control of PET
Determination of the diethylene glycol content, isophthalic acid content, intrinsic viscosity (ASTM D4603), and the acid number (AN) of polyethylene terephthalate (PET) is a lengthy and challenging process due to the sample’s limited solubility and the need to use different analytical methods. This application note demonstrates that the DS2500 Solid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a cost-efficient and fast solution for a simultaneous determination of these parameters in PET. Vis-NIR spectroscopy allows for the analysis of PET in less than one minute without sample preparation or using any chemical reagents.
AN-NIR-084
Quality Control of Silicone rubber
Determination of the vinyl content of silicone rubber is a lengthy and challenging process. First, the vinyl groups must be converted to ethylene by reacting with an acid, followed by the determination of the produced ethylene with gas chromatography (GC).This application note demonstrates that Vis-NIR (visible near-infrared) spectroscopy provides a cost-efficient and fast solution for the determination of vinyl content in silicone rubbers. With the DS2500 Solid Analyzer it is possible to obtain results in less than a minute without sample preparation or any chemical reagents.

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50 Insights

Apr 22, 2024
Titration – definition and principles
Titration is one of the oldest and well-established analytical methods. This blog covers the titration principle, its process, and presents different titration types.
Jun 13, 2022
Automation beyond the lab – Integrating the most precise lab pH measurements into production processes
Blog about pH sensors for process analysis with highly accurate results and low measurement uncertainty.
Apr 6, 2020
Improving your conductivity measurements
Tips and tricks on improving your conductivity measurements: choosing the right sensor, measuring the cell constant, standards, and more.
Nov 28, 2022
Save time and money with Metrohm Inline Sample Preparation solutions
When using ion chromatography (IC) as an analytical technique, samples often cannot be injected directly onto the separation column. Metrohm Inline Sample Preparation (MISP) techniques offer a broad spectrum of straightforward, cost- and time-saving solutions for these kinds of situations. This article gives an overview and some insights about MISP techniques—our solutions for automated inline sample preparation of various matrices for IC analysis.
May 31, 2021
Validation of titration methods
Learn more about titration method validation and USP 1225.
Apr 3, 2023
History and analysis of vitamin C (ascorbic acid)
This article covers the history of vitamin C (ascorbic acid) and some of the different analytical methods used to determine it in various products (e.g., by titration, polarography, and ion chromatography).
Jul 24, 2023
The world of surfactants from the perspective of titration
Accurately determining surfactant content in samples through potentiometric titration can be challenging, requiring the consideration of multiple factors. However, by selecting the appropriate pH, using a suitable electrode, and implementing helpful tips and tricks, the titration method becomes a reliable and precise means of surfactant content determination.
Oct 26, 2020
Thermometric titration – the missing piece of the puzzle
Blog post on thermometric titration measuring the enthalpy change of the reaction and the temperature change of the titration reaction.
Mar 6, 2023
Protecting IC systems with Metrohm Inline Ultrafiltration and Inline Dialysis
An efficient way to prepare samples for IC analysis is by using Metrohm Inline Sample Preparation (MISP) techniques to automate the process. Either Metrohm Inline Ultrafiltration (UF) or Inline Dialysis can be used to safeguard the IC system from harmful matrix components while simultaneously reducing manual labor and increasing sample throughput.
Feb 21, 2022
Ion selective electrodes general tips Part 1
Theory of ion measurement, types of ion-selective electrodes, why using TISAB or ISA solution for measuring ions, and more on our blog.